GreenScreen EM is a development of Gentronix’s core technology, specially formulated for monitoring both genotoxic and acutely toxic contaminants in aqueous samples, with applications in environmental monitoring and routine screening. The GreenScreen EM range comprises a convenient, disposable cuvette-based protocol with portable instrumentation and a microplate-based protocol for higher throughput screening. Aqueous samples are combined with GreenScreen yeast strains and assay medium, and after incubation, simple optical measurements are made. The yeast become increasingly fluorescent when exposed to genotoxic chemicals or contaminants, whilst cell proliferation is reduced by acute toxicity.
Genotoxins present in the environment can originate from a number of anthropogenic sources, such as chemical manufacturing plants, textile and dye industries, pulp and paper mills, petroleum refineries, landfill and waste disposal sites. The presence of genotoxins is of concern for the welfare of the environment and human health. In addition expanding legislation is resulting in increasingly stringent controls on effluent discharges, highlighting the inclusion of other indicators, such as genotoxicity, in standard monitoring requirements. Legislation such as the European Water Framework and IPPC Directives identify "substances or their breakdown products, which have carcinogenic or mutagenic properties", as a main pollutants of concern.
- Toxicity assessment of contaminated surface and ground waters
- Monitoring of industrial effluent discharges
- Screening of soil samples from contaminated land
- Tracing sources of environmental contamination
- Characterisation and monitoring of effluent treatment processes
- Toxicity profiling of environmentally relevant chemicals
Dr Andrew Knight
CTF Building 46 Grafton Street