Bio-test monitors benzene emissions
Chemical exposure has been a growing concern for over forty years. Although emission controls have improved considerably, demands for higher quality industrial and municipal life create a need for more comprehensive methods of chemical exposure measurement. Until now regulatory agencies have had to be satisfied with measuring concentrations of polluting agents in the environment around the exposed worker or citizen. However, as our understanding of the complex effects of exposure advances, so the demands for evaluating an individual's actual exposure increase.
Biological monitoring, or biomonitoring, is the measurement of a chemical or
its breakdown product in an exposed individual. Measurements may be made on
samples of breath, urine or blood and reflect the total uptake of the chemical
by inhalation, ingestion or absorption through the skin. Frustratingly, biomonitoring
methods have been slow, expensive and depended upon specialised scientific laboratories
and, consequently, were of limited accessibility.
Benzene, for example, is an important industrial chemical. High volumes, produced
in the petrol refining process and used by the chemical industry to manufacture
plastics, polystyrene and rubber, are released in to the atmosphere. Further,
emissions from automotive exhausts, cigarette smoke and landfill waste sites
contribute to the environmental load and chronic benzene exposure may lead to
cancers such as leukaemia.
A novel test for monitoring benzene exposure is now available through AB Biomonitoring.
The test uses a unique antibody to quantify a specific urinary metabolite of
benzene (S-phenylmercapturic acid). The test is reliable, robust and fully validated
in terms of analytical performance. Because of the speed and efficiency of the
test, many customers not only monitor workers after an accidental exposure but
have implemented routine screening programmes to protect the health of their
Moreover, the technology can be readily adapted for population screening where
there is concern about the impact of pollution on human health and quality of
life. Road traffic is one of the greatest threats to the environment, especially
in urban areas.
Environmental pollution is an immediate and urgent problem and environmental
consideration should possess a key role in selection and control processes.
This technology enables the wider application of biomonitoring as both a monitoring
and survey tool of environmental and industrial exposures. Affordable exposure
information will prevent disease, limit environmental damage and facilitate
the goals of sustainable development.
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